ILK Rabbit pAb
| Target | ILK |
|---|---|
| Product Type | Antibody |
| Application | IHC (P), WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ILK (NP_001014795.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.02% sodium azide,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded Protein A Affinity purificationssociates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. |
| Protocols | IHC (P), WB |
| Molecular Weight | 51kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |