QuickSwitch™ Quant HLA-A*02:01-APC and Peptides Bundle 2
The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
Target: Chain A, SARS-CoV-2 spike glycoprotein (1060-1068), Chain A, SARS-CoV-2 spike glycoprotein (424-433), Chain A, SARS-CoV-2 spike glycoprotein (691-699), ORF1ab polyprotein SARS-CoV-2 (5583-5591), SARS-CoV-2 ORF3a protein (107-115), SARS-CoV-2 Spike Glycoprotein
Product Type: Peptide, Tetramer
Application: FCM
Class: Class I
Species Reactivity: Human
Peptide Sequence: ISDEFSSNV, KLPDDFTGCV, RLNEVAKNL, RLQSLQTYV, SIIAYTMSL, VVFLHVTYV, YLQPRTFLL, YLYALVYFL
Research Area: Immunology, Immune Monitoring
Protocols: FCM
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.