Tetramer/BV421 – Mafa-A1*063 SIV nef RM9 (RPKVPLRTM)

Nonhuman primates (NHP) resemble humans in multiple ways including similarities in genomics,  immunogenetics, and age-related changes in immune function. These characteristics are critical to the establishment of a relevant model in which to conduct preclinical studies to optimize the efficacy and safety of  therapeutic approaches. Importantly, NHPs are vital preclinical models for viruses as viral infections are frequently associated with the same pathologies. Hence, NHPs are immune models to study viral vaccine efficacy and antiviral therapeutic safety and efficacy and to understand aspects of viral pathogenesis. Over numerous preclinical studies for human viral diseases, NHPs have demonstrated to be a beneficial benchmark for investigating human viral infections.

Target: SIV

Product Type: Tetramer

Application: FCM

Conjugate: BV421

Class: Class I

Species Reactivity: Cyno Macaque

Allele: Mafa-A1*063

Peptide Sequence: RPKVPLRTM

Research Area: Immunology, Immune Monitoring

Protocols: FCM

Specificity: nef RM9

Storage Temperature: 4°C

Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.