Anti-p62 C-terminal (Human) pAb (Polyclonal Antibody)

Polyclonal Antibody of 100 µl targeting p62 for IC, IH, IP, WB.

Target: p62

Product Type: Antibody

Application: IC, IH, IP, WB

Clonality: Polyclonal

Conjugate: Unlabeled

Isotype: Affinity Purified Ig

Immunogen: KLH conjugated human p62 C-terminus peptide

Host Species: Guinea Pig

Species Reactivity: Human, Hamster, Mouse, Rat

Formulation: PBS containing 50% Glycerol (pH 7.2). No preservative is contained.

Research Area: Autophagy

Description/Background: p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency.

Storage Temperature: This antibody solution is stable for one year from the date of purchase when stored at -20°C.

Protocols: IC, IH, IP, WB

Source: Purified Ig from Guinea Pig serum

Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.