Anti-HLA class I (HLA-A,B,C) (Human) mAb (Monoclonal Antibody)

Human major histocompatibility complex (MHC) class I antigen-epitope peptide complex associated with β2-microglobulin are expressed by all human nucleated cells. It plays an important role in cell-mediated immune responses. Abnormalities in MHC class I antigen surface expression are frequently found in malignancies and infectious diseases. They are often associated with reduced recognition by MHC class I antigen-restricted, tumor or virus-associated antigen-specific cytotoxic T lymphocytes and disease progression. The EMR8-5 monoclonal antibody reacts with a non-polymorphic epitope of human MHC class I antigens, HLA-A, -B, and -C.

Target: HLA class I

Product Type: Antibody

Application: FCM, IHC, WB

Clonality: Monoclonal

Conjugate: Unlabeled

Isotype: IgG1 κ

Species Reactivity: Human

Research Area: Immunology

Storage Temperature: -20°C

Protocols: FCM, IHC, WB

Clone Number: EMR8-5

Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.