Anti-SynCAM (TSLC1/CADM1) (Human) mAb

Monoclonal antibody targeting SynCAM/TSLC1 for FCM.

Target: SynCAM/TSLC1

Product Type: Antibody

Application: FCM

Clonality: Monoclonal

Conjugate: Unlabeled

Isotype: IgY

Immunogen: Recombinant SynCAM/Fc fusion protein

Host Species: Chicken

Species Reactivity: Human

Formulation: 100 µg IgG in 100 µL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

Research Area: Neuroscience

Description/Background:

SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts.

Storage Temperature: -20°C

Protocols: FCM

Clone Number: 9D2

Concentration: 1 mg/mL

Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.